By rail :

Situated on major TGV high-speed train lines, Poitiers is well situated, 1:30 hours from Paris, 1:45 hours from Bordeaux, 3:50 hours from Lyon and 3:15 hours from Lille.

SNCF

By road :
Both the A10 motorway, and route nationale 10 connect Poitiers to major cities (Paris : 350 km  / 178 miles, Bordeaux : 250 km / 135 miles).

By air :
From the Poitiers-Biard airport, regular connections are insured via Lyons airport, towards Metz/Nancy, Strasbourg, Stuttgart, Zurich, Mulhouse, Nice, Marseilles, Biarritz, Pau, Montpellier, Düsseldorf, Frankfurt, Munich, Venice, Bologna, Rome, Milan, and Barcelona.
Airport information